Gene
gatb
- ID
- ZDB-GENE-040724-131
- Name
- glutamyl-tRNA(Gln) amidotransferase, subunit B
- Symbol
- gatb Nomenclature History
- Previous Names
-
- pet112
- pet112l
- si:ch211-150a22.1
- zgc:103736
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Predicted to be involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Predicted to act upstream of or within translation. Predicted to be located in mitochondrion. Is expressed in serotonergic neurons. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 41. Orthologous to human GATB (glutamyl-tRNA amidotransferase subunit B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103736 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 41 | Alliance | ?Combined oxidative phosphorylation deficiency 41 | 618838 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006075 | Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic |
| Domain | IPR018027 | Asn/Gln amidotransferase |
| Family | IPR004413 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B |
| Family | IPR017959 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E |
| Homologous_superfamily | IPR003789 | Aspartyl/glutamyl-tRNA amidotransferase subunit B-like |
| Homologous_superfamily | IPR014746 | Glutamine synthetase/guanido kinase, catalytic domain |
| Homologous_superfamily | IPR023168 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 |
Domain Details Per Protein
| Protein | Length | Asn/Gln amidotransferase | Aspartyl/glutamyl-tRNA amidotransferase subunit B-like | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E | Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic | Glutamine synthetase/guanido kinase, catalytic domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7T010
|
553 |
Interactions and Pathways
No data available
Plasmids
No data available