Gene
syn2a
- ID
- ZDB-GENE-040718-341
- Name
- synapsin IIa
- Symbol
- syn2a Nomenclature History
- Previous Names
-
- syn2
- zgc:92311
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity. Predicted to be involved in neurotransmitter secretion. Predicted to localize to synaptic vesicle membrane. Human ortholog(s) of this gene implicated in schizophrenia. Is expressed in DEL; nervous system; spinal cord neural tube; and yolk syncytial layer. Orthologous to human SYN2 (synapsin II).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| schizophrenia | Alliance | {Schizophrenia, susceptibility to} | 181500 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR020897 | Synapsin, pre-ATP-grasp domain |
| Domain | IPR020898 | Synapsin, ATP-binding domain |
| Family | IPR001359 | Synapsin |
| Homologous_superfamily | IPR013815 | ATP-grasp fold, subdomain 1 |
| Homologous_superfamily | IPR016185 | Pre-ATP-grasp domain superfamily |
| PTM | IPR019736 | Synapsin, phosphorylation site |
Domain Details Per Protein
| Protein | Length | ATP-grasp fold, subdomain 1 | Pre-ATP-grasp domain superfamily | Synapsin | Synapsin, ATP-binding domain | Synapsin, phosphorylation site | Synapsin, pre-ATP-grasp domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R0A8
|
463 |
Interactions and Pathways
No data available
Plasmids
No data available