Gene
tnfsf10
- ID
- ZDB-GENE-040718-335
- Name
- TNF superfamily member 10
- Symbol
- tnfsf10 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity. Predicted to be involved in cell surface receptor signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within immune response. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in anterior lateral line neuromast; brain; and posterior lateral line neuromast. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Orthologous to human TNFSF10 (TNF superfamily member 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Eimon et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Serbanovic-Canic et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tumour necrosis factor, conserved site | Tumour necrosis factor domain | Tumour necrosis factor ligand 10/11 | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6DHG9
|
299 | ||||
|
UniProtKB:A0A2R8QAD8
|
286 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnfsf10-201
(1)
|
Ensembl | 1,879 nt | ||
| mRNA |
tnfsf10-202
(1)
|
Ensembl | 1,836 nt |
Interactions and Pathways
No data available
Plasmids
No data available