Gene
cdk5r1b
- ID
- ZDB-GENE-040718-220
- Name
- cyclin dependent kinase 5, regulatory subunit 1b (p35)
- Symbol
- cdk5r1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity and protein kinase binding activity. Acts upstream of or within amacrine cell differentiation; embryonic retina morphogenesis in camera-type eye; and retina layer formation. Predicted to be located in plasma membrane. Predicted to be part of protein kinase 5 complex. Predicted to be active in cytoplasm. Is expressed in basal plate midbrain region and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92814 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin-dependent kinase 5 activator | Cyclin-like superfamily |
|---|---|---|---|
|
UniProtKB:F1Q6W4
|
304 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdk5r1b-201
(1)
|
Ensembl | 1,385 nt |
Interactions and Pathways
No data available
Plasmids
No data available