Gene
ltv1
- ID
- ZDB-GENE-040712-1
- Name
- LTV1 ribosome biogenesis factor
- Symbol
- ltv1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Involved in definitive hemopoiesis; digestive system development; and ribosome biogenesis. Acts upstream of or within cartilage morphogenesis and rRNA processing. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including digestive system; eye; immature eye; midbrain; and segmental plate. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103432 (20 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory poikiloderma with hair abnormalities and acral keratoses | Alliance | Inflammatory poikiloderma with hair abnormalities and acral keratoses | 620199 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007307 | Low temperature viability protein Ltv1 |
Domain Details Per Protein
| Protein | Length | Low temperature viability protein Ltv1 |
|---|---|---|
|
UniProtKB:F1R9T9
|
473 | |
|
UniProtKB:Q5U3J8
|
469 | |
|
UniProtKB:A0A8M9PP26
|
472 |
Interactions and Pathways
No data available
Plasmids
No data available