Gene

prpf18

ID
ZDB-GENE-040704-45
Name
PRP18 pre-mRNA processing factor 18 homolog (yeast)
Symbol
prpf18 Nomenclature History
Previous Names
  • zgc:91830
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to contribute to second spliceosomal transesterification activity. Predicted to be involved in generation of catalytic spliceosome for second transesterification step and nuclear retention of unspliced pre-mRNA at the site of transcription. Predicted to localize to U2-type post-spliceosomal complex; U4/U6 x U5 tri-snRNP complex; and U5 snRNP. Orthologous to human PRPF18 (pre-mRNA processing factor 18).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prpf18 Human Ortholog
No data available
Associated With prpf18 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004098 Prp18
Domain IPR014906 Pre-mRNA processing factor 4 (PRP4)-like
Family IPR039979 Pre-mRNA-splicing factor 18
Homologous_superfamily IPR036285 PRP4-like superfamily
Domain Details Per Protein
Protein Length Pre-mRNA processing factor 4 (PRP4)-like Pre-mRNA-splicing factor 18 Prp18 PRP4-like superfamily
UniProtKB:A0A8M9PFD4 351
UniProtKB:Q6GMH0 342
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prpf18-201 (1) Ensembl 1,530 nt
mRNA prpf18-202 (1) Ensembl 1,056 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations