Gene
cep41
- ID
- ZDB-GENE-040704-35
- Name
- centrosomal protein 41
- Symbol
- cep41 Nomenclature History
- Previous Names
-
- tsga14
- zgc:91859
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Enables tubulin-glutamic acid ligase activity. Involved in cilium assembly and protein polyglutamylation. Acts upstream of or within axoneme assembly and neural crest cell migration. Predicted to be located in centriole and cilium. Predicted to be active in ciliary basal body. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; immature eye; nervous system; and pronephric duct. Human ortholog(s) of this gene implicated in Joubert syndrome 15. Orthologous to human CEP41 (centrosomal protein 41).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91859 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Joubert syndrome 15 | Alliance | Joubert syndrome 15 | 614464 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Centrosomal protein 41 | Rhodanese-like domain | Rhodanese-like domain superfamily |
|---|---|---|---|---|
|
UniProtKB:Q6GQN0
|
374 |
Interactions and Pathways
No data available
Plasmids
No data available