Gene

brk1

ID
ZDB-GENE-040625-77
Name
BRICK1 subunit of SCAR/WAVE actin nucleating complex
Symbol
brk1 Nomenclature History
Previous Names
  • zgc:86903
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to be involved in cell motility and regulation of actin polymerization or depolymerization. Predicted to localize to SCAR complex. Orthologous to human BRK1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Edwards et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With brk1 Human Ortholog
No data available
Associated With brk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR033378 Protein BRICK1
Domain Details Per Protein
Protein Length Protein BRICK1
UniProtKB:Q6IQ86 75
UniProtKB:A8WG56 75
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA brk1-201 (1) Ensembl 878 nt
mRNA brk1-202 (1) Ensembl 1,414 nt
mRNA brk1-203 (1) Ensembl 1,902 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations