Gene

idh3b

ID

ZDB-GENE-040625-174

Name

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

Symbol

idh3b Nomenclature History

Previous Names

zgc:86647

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in retinitis pigmentosa 46. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; optic tectum; and pronephric duct. Orthologous to human IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6905633 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With idh3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 46	Alliance	Retinitis pigmentosa 46	612572

Associated With idh3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019818	Isocitrate/isopropylmalate dehydrogenase, conserved site
Domain	IPR024084	Isopropylmalate dehydrogenase-like domain
Family	IPR004434	Isocitrate dehydrogenase NAD-dependent