Gene
dact1
- ID
- ZDB-GENE-040623-3
- Name
- dishevelled-binding antagonist of beta-catenin 1
- Symbol
- dact1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Involved in Wnt signaling pathway. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome. Is expressed in several structures, including germ ring; immature eye; mesoderm; nervous system; and neural plate. Orthologous to human DACT1 (dishevelled binding antagonist of beta catenin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu31 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Waxman et al., 2004
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Townes-Brocks syndrome 2 | 617466 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR024843 | Dapper |
Domain Details Per Protein
| Protein | Length | Dapper |
|---|---|---|
|
UniProtKB:Q6QZN6
|
821 | |
|
UniProtKB:A0A8M1PR00
|
821 |
Interactions and Pathways
No data available
Plasmids