Gene
pth1b
- ID
- ZDB-GENE-040623-2
- Name
- parathyroid hormone 1b
- Symbol
- pth1b Nomenclature History
- Previous Names
-
- pth2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits hormone activity. Predicted to be involved in cellular calcium ion homeostasis. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Is expressed in heart; immune system; integument; muscle; and nervous system. Orthologous to human PTH (parathyroid hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial isolated hypoparathyroidism | Alliance | Hypoparathyroidism, familial isolated 1 | 146200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Parathyroid hormone | Parathyroid hormone/parathyroid hormone-related protein |
|---|---|---|---|
|
UniProtKB:Q6WQ24
|
99 |
Interactions and Pathways
No data available
Plasmids
No data available