Gene
pth1a
- ID
- ZDB-GENE-040623-1
- Name
- parathyroid hormone 1a
- Symbol
- pth1a Nomenclature History
- Previous Names
-
- pth1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Exhibits hormone activity. Involved in calcium ion homeostasis and epidermal cell differentiation. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Is expressed in several structures, including gill; heart; integument; nervous system; and pleuroperitoneal region. Orthologous to human PTH (parathyroid hormone).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial isolated hypoparathyroidism | Alliance | Hypoparathyroidism, familial isolated 1 | 146200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Parathyroid hormone | Parathyroid hormone/parathyroid hormone-related protein |
|---|---|---|---|
|
UniProtKB:Q6WQ25
|
102 |
Interactions and Pathways
No data available
Plasmids
No data available