Gene
esrrb
- ID
- ZDB-GENE-040616-2
- Name
- estrogen-related receptor beta
- Symbol
- esrrb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have several functions, including DNA-binding transcription factor activity; steroid hormone receptor activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 35. Is expressed in basal plate midbrain region; nervous system; and pronephric duct. Orthologous to human ESRRB (estrogen related receptor beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- ay556396 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 35 | Alliance | Deafness, autosomal recessive 35 | 608565 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR024178 | Estrogen receptor/oestrogen-related receptor |
| Family | IPR027289 | Oestrogen-related receptor |
| Family | IPR050200 | Nuclear hormone receptor family NR3 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Estrogen receptor/oestrogen-related receptor | Nuclear hormone receptor | Nuclear hormone receptor family NR3 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Oestrogen-related receptor | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1P2J7
|
437 | ||||||||
|
UniProtKB:Q6Q6F5
|
340 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available