Gene

nr1d2a

ID

ZDB-GENE-040504-1

Name

nuclear receptor subfamily 1, group D, member 2a

Symbol

nr1d2a Nomenclature History

Previous Names

NR1D2-A (1)
nr1d2a (1)
Rev-Erb Beta 1 (1)
reverbb1
Reverbbeta-A (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have several functions, including nuclear receptor activity; steroid hormone receptor activity; and zinc ion binding activity. Involved in circadian regulation of gene expression and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in nervous system. Orthologous to human NR1D2 (nuclear receptor subfamily 1 group D member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

af342941 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nr1d2a Human Ortholog

No data available

Associated With nr1d2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Family	IPR001723	Nuclear hormone receptor
Family	IPR001728	Thyroid hormone receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily

Domain Details Per Protein

Protein	Length	Nuclear hormone receptor	Nuclear hormone receptor, ligand-binding domain	Nuclear hormone receptor-like domain superfamily	Thyroid hormone receptor	Zinc finger, NHR/GATA-type	Zinc finger, nuclear hormone receptor-type
UniProtKB:F1QIC9 InterPro	504

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nr1d2a-201 (1) Ensembl	Ensembl	3,081 nt	Select Tool ZFIN BLAST
mRNA	nr1d2a-203 (1) Ensembl	Ensembl	3,995 nt	Select Tool ZFIN BLAST
ncRNA	nr1d2a-002 (1) Ensembl	Ensembl	450 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations