Gene

xpnpep1

ID

ZDB-GENE-040426-999

Name

X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

Symbol

xpnpep1 Nomenclature History

Previous Names

fa02e02
wu:fa02e02
zgc:56366
zgc:77772 (1)

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity and metalloaminopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Is expressed in intestine and liver. Orthologous to human XPNPEP1 (X-prolyl aminopeptidase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7136461 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With xpnpep1 Human Ortholog

No data available

Associated With xpnpep1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000587	Creatinase, N-terminal
Domain	IPR000994	Peptidase M24
Domain	IPR032416	Peptidase M24, C-terminal domain
Domain	IPR033740	Aminopeptidase P
Family	IPR050422	Xaa-Pro aminopeptidase P
Homologous_superfamily	IPR029149	Creatinase/Aminopeptidase P/Spt16, N-terminal
Homologous_superfamily	IPR036005	Creatinase/aminopeptidase-like

Domain Details Per Protein

Protein	Length	Aminopeptidase P	Creatinase/aminopeptidase-like	Creatinase/Aminopeptidase P/Spt16, N-terminal	Creatinase, N-terminal	Peptidase M24	Peptidase M24, C-terminal domain	Xaa-Pro aminopeptidase P
UniProtKB:A0A286Y8E9 InterPro	625
UniProtKB:Q6P1S3 InterPro	620

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	xpnpep1-201 (1) Ensembl	Ensembl	2,153 nt	Select Tool
mRNA	xpnpep1-202 (1) Ensembl	Ensembl	963 nt	Select Tool
mRNA	xpnpep1-203 (1) Ensembl	Ensembl	2,086 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations