Gene

odad4

ID

ZDB-GENE-040426-995

Name

outer dynein arm docking complex subunit 4

Symbol

odad4 Nomenclature History

Previous Names

ttc25
zgc:56362 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Involved in cilium assembly; determination of heart left/right asymmetry; and otolith morphogenesis. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 35. Is expressed in several structures, including central nervous system; forerunner cell group; otic placode; pronephric duct; and pronephric mesoderm. Orthologous to human TTC25 (tetratricopeptide repeat domain 25).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56362 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Xu et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With odad4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
primary ciliary dyskinesia 35	Alliance	Ciliary dyskinesia, primary, 35	617092

Associated With odad4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR040111	Outer dynein arm-docking complex subunit 4
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR019734	Tetratricopeptide repeat