Gene
cox15
- ID
- ZDB-GENE-040426-955
- Name
- cytochrome c oxidase assembly homolog 15 (yeast)
- Symbol
- cox15 Nomenclature History
- Previous Names
-
- wu:fa18g06
- zgc:56240
- zgc:77422
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme a biosynthetic process. Predicted to localize to mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 6 | Alliance | Mitochondrial complex IV deficiency, nuclear type 6 | 615119 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | COX15/CtaA family | Heme A synthase, type 2 | Peptidase S1, PA clan |
|---|---|---|---|---|
|
UniProtKB:F1R355
|
399 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available