Gene
pex12
- ID
- ZDB-GENE-040426-929
- Name
- peroxisomal biogenesis factor 12
- Symbol
- pex12 Nomenclature History
- Previous Names
-
- zgc:56182
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin-protein transferase activity. Predicted to be involved in protein import into peroxisome matrix and protein monoubiquitination. Predicted to localize to integral component of peroxisomal membrane and peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 3A. Orthologous to human PEX12 (peroxisomal biogenesis factor 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| peroxisome biogenesis disorder 3A | Alliance | Peroxisome biogenesis disorder 3A (Zellweger) | 614859 |
| peroxisome biogenesis disorder 3B | Alliance | Peroxisome biogenesis disorder 3B | 266510 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Peroxisome assembly protein 12 | Pex, N-terminal | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|
|
UniProtKB:B0R157
|
350 |
Interactions and Pathways
No data available
Plasmids
No data available