Gene

smu1a

ID

ZDB-GENE-040426-916

Name

SMU1 DNA replication regulator and spliceosomal factor a

Symbol

smu1a Nomenclature History

Previous Names

smu1
zgc:56147 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to be involved in mRNA splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within mRNA processing. Predicted to be located in nuclear speck. Predicted to be part of U2-type precatalytic spliceosome. Orthologous to human SMU1 (SMU1 DNA replication regulator and spliceosomal factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56147 (1 image)
IMAGE:6911577 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smu1a Human Ortholog

No data available

Associated With smu1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006594	LIS1 homology motif
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR006595	CTLH, C-terminal LisH motif
Domain	IPR054532	TPL/SMU1, LisH-like dimerisation domain
Family	IPR045184	WD40 repeat-containing protein SMU1
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Length	CTLH, C-terminal LisH motif	G-protein beta WD-40 repeat	LIS1 homology motif	TPL/SMU1, LisH-like dimerisation domain	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40 repeat-containing protein SMU1	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q7ZVA0 InterPro	513

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	smu1a-201 (1) Ensembl	Ensembl	1,934 nt	Select Tool ZFIN BLAST
ncRNA	smu1a-002 (1) Ensembl	Ensembl	754 nt	Select Tool ZFIN BLAST
ncRNA	smu1a-003 (1) Ensembl	Ensembl	754 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations