Gene
cyp2p6
- ID
- ZDB-GENE-040426-790
- Name
- cytochrome P450, family 2, subfamily P, polypeptide 6
- Symbol
- cyp2p6 Nomenclature History
- Previous Names
-
- cyp2j1 (1)
- cyp2j25
- si:dkey-183n20.5
- zgc:55731
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension; myocardial infarction; pulmonary hypertension; renal fibrosis; and renal hypertension. Is expressed in brain; gonad; heart; kidney; and trunk musculature. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017972 | Cytochrome P450, conserved site |
| Family | IPR001128 | Cytochrome P450 |
| Family | IPR002401 | Cytochrome P450, E-class, group I |
| Family | IPR008069 | Cytochrome P450, E-class, group I, CYP2D-like |
| Family | IPR050182 | Cytochrome P450 family 2 |
| Homologous_superfamily | IPR036396 | Cytochrome P450 superfamily |
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450, E-class, group I, CYP2D-like | Cytochrome P450 family 2 | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q803J0
|
496 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp2p6-201
(1)
|
Ensembl | 2,498 nt |
Interactions and Pathways
No data available
Plasmids
No data available