Gene

atf3

ID

ZDB-GENE-040426-728

Name

activating transcription factor 3

Symbol

atf3 Nomenclature History

Previous Names

zgc:55526 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in response to virus. Predicted to localize to nucleus. Is expressed in brain; eye; and retina. Orthologous to human ATF3 (activating transcription factor 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

24 figures from 16 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Yin et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atf3 Human Ortholog

No data available

Associated With atf3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Family	IPR000837	AP-1 transcription factor
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily