Gene
fzr1a
- ID
- ZDB-GENE-040426-712
- Name
- fizzy/cell division cycle 20 related 1a
- Symbol
- fzr1a Nomenclature History
- Previous Names
-
- fzr1
- zgc:55450
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have anaphase-promoting complex binding activity and ubiquitin-protein transferase activator activity. Predicted to be involved in cell division and positive regulation of ubiquitin protein ligase activity. Orthologous to human FZR1 (fizzy and cell division cycle 20 related 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55450 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Imai et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 109 | Alliance | Developmental and epileptic encephalopathy 109 | 620145 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR024977 | Anaphase-promoting complex subunit 4-like, WD40 domain |
| Family | IPR033010 | WD repeat Cdc20/Fizzy |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | Anaphase-promoting complex subunit 4-like, WD40 domain | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat Cdc20/Fizzy |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZUP9
|
495 |
Interactions and Pathways
No data available
Plasmids
No data available