Gene

ccn1

ID

ZDB-GENE-040426-3

Name

cellular communication network factor 1

Symbol

ccn1 Nomenclature History

Previous Names

cyr61
zCyr61-c23 (1)
zgc:85866

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable heparin binding activity and integrin binding activity. Acts upstream of or within fin regeneration. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Is expressed in several structures, including brain; endocrine system; epidermis; hypochord; and neural plate. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human CCN1 (cellular communication network factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 9 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:85866 (23 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ccn1 Human Ortholog

No data available

Associated With ccn1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000867	Insulin-like growth factor-binding protein, IGFBP
Domain	IPR001007	VWFC domain
Domain	IPR006207	Cystine knot, C-terminal
Domain	IPR006208	Glycoprotein hormone subunit beta
Domain	IPR043973	CCN, TSP1 domain
Family	IPR012395	IGFBP-related, CNN
Family	IPR050941	Cellular Communication Network Factor
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat