Gene

creb3l3l

ID

ZDB-GENE-040426-2942

Name

cAMP responsive element binding protein 3-like 3 like

Symbol

creb3l3l Nomenclature History

Previous Names

creb3l3 (1)
wu:fj05f07
zgc:66452

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity and cAMP response element binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in central nervous system; liver; notochord; sensory system; and yolk syncytial layer. Orthologous to human CREB3 (cAMP responsive element binding protein 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66452 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With creb3l3l Human Ortholog

No data available

Associated With creb3l3l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Family	IPR051381	cAMP-responsive element-binding ATF subfamily
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily

Domain Details Per Protein

Protein	Length	Basic-leucine zipper domain	Basic-leucine zipper domain superfamily	cAMP-responsive element-binding ATF subfamily
UniProtKB:A0A8M2BEK7 InterPro	468

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	creb3l3l-201 (1) Ensembl	Ensembl	2,527 nt	Select Tool ZFIN BLAST
mRNA	creb3l3l-202 (1) Ensembl	Ensembl	839 nt	Select Tool ZFIN BLAST
ncRNA	creb3l3l-003 (1) Ensembl	Ensembl	591 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl
Note: Woods, et al. (2005. Genome Res. 15:1307-1914.) stated orthology to CREB3L3 supported by amino acid sequence identity. Subsequent data supported that a different gene (ZDB-GENE-030131-4298) is the ortholog of human CREB3L3 based on higher amino acid sequence identity as well as conserved location.

Citations