Gene
mapk4
- ID
- ZDB-GENE-040426-2835
- Name
- mitogen-activated protein kinase 4
- Symbol
- mapk4 Nomenclature History
- Previous Names
-
- ERK4 (1)
- wu:fi27d11
- zgc:55498
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have MAP kinase activity. Predicted to be involved in cellular response to organic substance; intracellular signal transduction; and regulation of gene expression. Predicted to localize to cytoplasm and nucleus. Is expressed in brain; digestive system; otic vesicle; post-vent region; and retina. Orthologous to human MAPK4 (mitogen-activated protein kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Krens et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR008350 | Mitogen-activated protein (MAP) kinase, ERK3/4 |
| Family | IPR050117 | Mitogen-activated protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Mitogen-activated protein kinase | Mitogen-activated protein (MAP) kinase, ERK3/4 | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B0V360
|
674 | ||||||
|
UniProtKB:Q803M9
|
674 |
Interactions and Pathways
No data available
Plasmids
No data available