Gene
derl1
- ID
- ZDB-GENE-040426-2793
- Name
- derlin 1
- Symbol
- derl1 Nomenclature History
- Previous Names
-
- wu:fb09d07
- wu:fb94d05
- wu:fj92g12
- zgc:55637 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have misfolded protein binding activity and ubiquitin-specific protease binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and ubiquitin-dependent ERAD pathway. Predicted to localize to Hrd1p ubiquitin ligase ERAD-L complex and integral component of endoplasmic reticulum membrane. Is expressed in liver. Orthologous to human DERL1 (derlin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55637 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Saslowsky et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Derlin | Rhomboid-like superfamily |
|---|---|---|---|
|
UniProtKB:F1Q4W3
|
261 |
Interactions and Pathways
No data available
Plasmids
No data available