Gene
plrg1
- ID
- ZDB-GENE-040426-2787
- Name
- pleiotropic regulator 1
- Symbol
- plrg1 Nomenclature History
- Previous Names
-
- wu:fi74f01
- zgc:55651
- zgc:86603
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Acts upstream of or within negative regulation of DNA damage response, signal transduction by p53 class mediator and negative regulation of apoptotic process. Predicted to be part of Prp19 complex and catalytic step 2 spliceosome. Orthologous to human PLRG1 (pleiotropic regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138004 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR045241 | WD repeat Prp46/PLRG1-like |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat Prp46/PLRG1-like |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DRE2
|
511 |
Interactions and Pathways
No data available
Plasmids
No data available