Gene

ugt1ab

ID

ZDB-GENE-040426-2762

Name

UDP glucuronosyltransferase 1 family a, b

Symbol

ugt1ab Nomenclature History

Previous Names

ugt1a3
zgc:123097
zgc:66393

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Exhibits glucuronosyltransferase activity. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Is expressed in intestinal bulb; intestine; liver; renal system; and testis. Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:112502 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ugt1ab Human Ortholog

No data available

Associated With ugt1ab Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR035595	UDP-glycosyltransferase family, conserved site
Family	IPR002213	UDP-glucuronosyl/UDP-glucosyltransferase
Family	IPR050271	UDP-glycosyltransferase

Domain Details Per Protein

Protein	Length	UDP-glucuronosyl/UDP-glucosyltransferase	UDP-glycosyltransferase	UDP-glycosyltransferase family, conserved site
UniProtKB:F1R1P2 InterPro	536
UniProtKB:A0A2R8QML4 InterPro

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ugt1a1-203 (1) Ensembl	Ensembl	1,106 nt	Select Tool ZFIN BLAST
mRNA	ugt1a1-209 (1) Ensembl	Ensembl	1,082 nt	Select Tool ZFIN BLAST
mRNA	ugt1a1-210 (1) Ensembl	Ensembl	1,103 nt	Select Tool ZFIN BLAST
mRNA	ugt1a1-211 (1) Ensembl	Ensembl	1,042 nt	Select Tool ZFIN BLAST
mRNA	ugt1a2-201 (1) Ensembl	Ensembl	1,964 nt	Select Tool
mRNA	ugt1a2-202 (1) Ensembl	Ensembl	1,872 nt	Select Tool
mRNA	ugt1a2-204 (1) Ensembl	Ensembl	1,546 nt	Select Tool
mRNA	ugt1a2-205 (1) Ensembl	Ensembl	1,563 nt	Select Tool
mRNA	ugt1a2-206 (1) Ensembl	Ensembl	1,563 nt	Select Tool
mRNA	ugt1a2-207 (1) Ensembl	Ensembl	1,918 nt	Select Tool
mRNA	ugt1a2-208 (1) Ensembl	Ensembl	1,563 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations