Gene

adgrl4

ID

ZDB-GENE-040426-2689

Name

adhesion G protein-coupled receptor L4

Symbol

adgrl4 Nomenclature History

Previous Names

eltd1
fd10a02
wu:fd10a02
zgc:63629

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; eye; liver; pleuroperitoneal region; and ventral mesoderm. Orthologous to human ADGRL4 (adhesion G protein-coupled receptor L4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7138992 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adgrl4 Human Ortholog

No data available

Associated With adgrl4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR000203	GPS motif
Conserved_site	IPR017983	GPCR, family 2, secretin-like, conserved site
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR017981	GPCR, family 2-like, 7TM
Domain	IPR032471	GAIN domain, N-terminal
Domain	IPR049883	NOTCH1 EGF-like calcium-binding domain
Family	IPR000832	GPCR, family 2, secretin-like
Homologous_superfamily	IPR046338	GAIN domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site