Gene

msmo1

ID

ZDB-GENE-040426-2670

Name

methylsterol monooxygenase 1

Symbol

msmo1 Nomenclature History

Previous Names

koliber (1)
sc4mol
wu:fb59g06
wu:fb66e06
zgc:56437

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have C-4 methylsterol oxidase activity. Predicted to be involved in sterol biosynthetic process. Predicted to localize to endoplasmic reticulum membrane. Is expressed in epidermis; head; lens; and otic vesicle. Orthologous to human MSMO1 (methylsterol monooxygenase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from Anderson et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With msmo1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Microcephaly, congenital cataract, and psoriasiform dermatitis	616834

Associated With msmo1 Via Experimental Models

Human Disease	Fish	Conditions	Citations
chondrodysplasia punctata	msmo1^nu81/+; msmo1^nu7/+	standard conditions	Anderson et al., 2020
chondrodysplasia punctata	msmo1^nu7/nu7	standard conditions	Anderson et al., 2020