Gene

aimp2

ID

ZDB-GENE-040426-2652

Name

aminoacyl tRNA synthetase complex interacting multifunctional protein 2

Symbol

aimp2 Nomenclature History

Previous Names

wu:fc09d04
zgc:63976

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to localize to aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Is expressed in several structures, including alar plate midbrain region; head; immature eye; midbrain; and musculature system. Orthologous to human AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63976 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aimp2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hypomyelinating leukodystrophy 17	Alliance	Leukodystrophy, hypomyelinating, 17	618006

Associated With aimp2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004046	Glutathione S-transferase, C-terminal
Domain	IPR031889	AIMP2, lysyl-tRNA synthetase binding domain
Domain	IPR041503	AIMP2, thioredoxin-like domain
Family	IPR042360	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Homologous_superfamily	IPR036282	Glutathione S-transferase, C-terminal domain superfamily