Gene
ehhadh
- ID
- ZDB-GENE-040426-2581
- Name
- enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
- Symbol
- ehhadh Nomenclature History
- Previous Names
-
- l-pbe (1)
- zgc:77526
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable delta(3)-delta(2)-enoyl-CoA isomerase activity; enoyl-CoA hydratase activity; and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be active in peroxisome. Is expressed in male organism. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 3. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77526 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi renotubular syndrome 3 | Alliance | ?Fanconi renotubular syndrome 3 | 615605 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR006180 | 3-hydroxyacyl-CoA dehydrogenase, conserved site |
| Conserved_site | IPR018376 | Enoyl-CoA hydratase/isomerase, conserved site |
| Domain | IPR006108 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal |
| Domain | IPR006176 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding |
| Family | IPR001753 | Enoyl-CoA hydratase/isomerase |
| Homologous_superfamily | IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily |
| Homologous_superfamily | IPR029045 | ClpP/crotonase-like domain superfamily |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | 3-hydroxyacyl-CoA dehydrogenase, conserved site | 3-hydroxyacyl-CoA dehydrogenase, C-terminal | 3-hydroxyacyl-CoA dehydrogenase, NAD binding | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | ClpP/crotonase-like domain superfamily | Enoyl-CoA hydratase/isomerase | Enoyl-CoA hydratase/isomerase, conserved site | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYL3
|
718 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ehhadh-201
(1)
|
Ensembl | 2,480 nt |
Interactions and Pathways
No data available
Plasmids
No data available