Gene
wfikkn1
- ID
- ZDB-GENE-040426-2465
- Name
- WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
- Symbol
- wfikkn1 Nomenclature History
- Previous Names
-
- Gasp2 (1)
- zgc:85816
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have metalloendopeptidase inhibitor activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of peptidase activity. Predicted to localize to extracellular region. Orthologous to human WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85816 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shankar et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020901 | Proteinase inhibitor I2, Kunitz, conserved site |
| Domain | IPR001134 | Netrin domain |
| Domain | IPR002223 | Pancreatic trypsin inhibitor Kunitz domain |
| Domain | IPR002350 | Kazal domain |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR008197 | WAP-type 'four-disulfide core' domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR018933 | Netrin module, non-TIMP type |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR036645 | Elafin-like superfamily |
| Homologous_superfamily | IPR036880 | Pancreatic trypsin inhibitor Kunitz domain superfamily |
Domain Details Per Protein
| Protein | Length | Elafin-like superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Kazal domain | Kazal domain superfamily | Netrin domain | Netrin module, non-TIMP type | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | Proteinase inhibitor I2, Kunitz, conserved site | Tissue inhibitor of metalloproteinases-like, OB-fold | WAP-type 'four-disulfide core' domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NUX0
|
558 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wfikkn1-201
(1)
|
Ensembl | 2,270 nt | ||
| mRNA |
wfikkn1-202
(1)
|
Ensembl | 1,335 nt |
Interactions and Pathways
No data available
Plasmids
No data available