Gene
ift122
- ID
- ZDB-GENE-040426-2449
- Name
- intraflagellar transport 122 homolog (Chlamydomonas)
- Symbol
- ift122 Nomenclature History
- Previous Names
-
- zgc:77217 (1)
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Involved in several processes, including animal organ development; melanosome transport; and opsin transport. Predicted to localize to ciliary basal body; intraciliary transport particle A; and non-motile cilium. Used to study retinal degeneration. Human ortholog(s) of this gene implicated in Sensenbrenner syndrome. Is expressed in several structures, including nervous system; neural plate; neural rod; pronephric duct; and pronephric mesoderm. Orthologous to human IFT122 (intraflagellar transport 122).
- Genome Resources
-
- Alliance (1)
- Gene:405826 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77217 (14 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cranioectodermal dysplasia 1 | Alliance | Cranioectodermal dysplasia 1 | 218330 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| retinal degeneration | ift122jj263/jj263 | standard conditions | Boubakri et al., 2016 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intraflagellar transport protein 122/121 homolog | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6NYH1
|
1187 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance