Gene
spred1
- ID
- ZDB-GENE-040426-2338
- Name
- sprouty related EVH1 domain containing 1
- Symbol
- spred1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have protein kinase binding activity. Involved in blood vessel morphogenesis; lymph vessel development; and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to localize to membrane. Orthologous to human SPRED1 (sprouty related EVH1 domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85707 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Legius syndrome | Alliance | Legius syndrome | 611431 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | c-Kit-binding domain | PH-like domain superfamily | SPRE, EVH1 domain | Sprouty | WH1/EVH1 domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6NV01
|
391 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spred1-201
(1)
|
Ensembl | 3,432 nt | ||
| mRNA |
spred1-202
(1)
|
Ensembl | 2,545 nt |
Interactions and Pathways
No data available
Plasmids