Gene
pla2g7
- ID
- ZDB-GENE-040426-2248
- Name
- phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
- Symbol
- pla2g7 Nomenclature History
- Previous Names
-
- zgc:77563 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have 1-alkyl-2-acetylglycerophosphocholine esterase activity. Predicted to be involved in lipid catabolic process. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Is expressed in lens and solid lens vesicle. Orthologous to several human genes including PLA2G7 (phospholipase A2 group VII).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77563 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Platelet-activating factor acetylhydrolase deficiency | 614278 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Platelet-activating factor acetylhydrolase-like, eukaryote |
|---|---|---|---|
|
UniProtKB:Q6NYI7
|
404 | ||
|
UniProtKB:Q5RHM0
|
444 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pla2g7-201
(1)
|
Ensembl | 2,602 nt | ||
| mRNA |
pla2g7-202
(1)
|
Ensembl | 721 nt | ||
| ncRNA |
pla2g7-002
(1)
|
Ensembl | 493 nt |
Interactions and Pathways
No data available
Plasmids
No data available