Gene

map1lc3a

ID
ZDB-GENE-040426-2232
Name
microtubule-associated protein 1 light chain 3 alpha
Symbol
map1lc3a Nomenclature History
Previous Names
  • zgc:77094
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable microtubule binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in autophagosome assembly; autophagy of mitochondrion; and cellular response to nitrogen starvation. Predicted to act upstream of or within autophagy. Predicted to be located in membrane. Predicted to be active in autophagosome membrane and cytosol. Is expressed in forerunner cell group; nervous system; neural tube; and tail bud. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map1lc3a Human Ortholog
No data available
Associated With map1lc3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004241 Autophagy protein Atg8 ubiquitin-like
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Domain Details Per Protein
Protein Length Autophagy protein Atg8 ubiquitin-like Ubiquitin-like domain superfamily
UniProtKB:Q6NX90 121
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA map1lc3a-201 (1) Ensembl 1,511 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations