Gene
eif5a
- ID
- ZDB-GENE-040426-2229
- Name
- eukaryotic translation initiation factor 5A
- Symbol
- eif5a Nomenclature History
- Previous Names
-
- wu:fb17e01
- wu:fb63h04
- wu:fk81e04
- zgc:77099
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have translation elongation factor activity. Predicted to be involved in positive regulation of translational elongation. Is expressed in endoderm; intestine; liver; pancreas; and swim bladder. Orthologous to several human genes including EIF5A (eukaryotic translation initiation factor 5A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909077 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Faundes-Banka syndrome | 619376 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR020189 | Translation elongation factor, IF5A C-terminal |
| Domain | IPR048670 | Translation initiation factor 5A-like, N-terminal |
| Family | IPR001884 | Translation elongation factor IF5A-like |
| Homologous_superfamily | IPR008991 | Translation protein SH3-like domain superfamily |
| Homologous_superfamily | IPR012340 | Nucleic acid-binding, OB-fold |
| Homologous_superfamily | IPR014722 | Large ribosomal subunit protein uL2, domain 2 |
| PTM | IPR019769 | Translation elongation factor, IF5A, hypusine site |
Domain Details Per Protein
| Protein | Length | Large ribosomal subunit protein uL2, domain 2 | Nucleic acid-binding, OB-fold | Translation elongation factor, IF5A C-terminal | Translation elongation factor, IF5A, hypusine site | Translation elongation factor IF5A-like | Translation initiation factor 5A-like, N-terminal | Translation protein SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NX89
|
155 |
Interactions and Pathways
No data available
Plasmids
No data available