Gene

sumo1

ID

ZDB-GENE-040426-2186

Name

small ubiquitin like modifier 1

Symbol

sumo1 Nomenclature History

Previous Names

fd12c02
hm:zeh0670
wu:fb74c02
wu:fd12c02 (1)
zgc:65934
zgc:85634 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable protein tag and ubiquitin-like protein ligase binding activity. Acts upstream of or within chordate embryonic development and definitive hemopoiesis. Predicted to be located in nuclear stress granule. Predicted to be active in nucleus. Predicted to colocalize with PML body. Is expressed in brain; cranial neural crest cell; digestive system; eye; and pectoral fin bud. Human ortholog(s) of this gene implicated in orofacial cleft 10. Orthologous to several human genes including SUMO1 (small ubiquitin like modifier 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6907399 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sumo1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
orofacial cleft 10	Alliance	?Orofacial cleft 10	613705

Associated With sumo1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000626	Ubiquitin-like domain
Domain	IPR022617	Rad60/SUMO-like domain
Domain	IPR046332	Small ubiquitin-related modifier 1, Ubl domain
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily