Gene

arih2

ID
ZDB-GENE-040426-2158
Name
ariadne homolog 2 (Drosophila)
Symbol
arih2 Nomenclature History
Previous Names
  • wu:fa09c12
  • zgc:64093
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm and ubiquitin ligase complex. Orthologous to human ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arih2 Human Ortholog
No data available
Associated With arih2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001841 Zinc finger, RING-type
Domain IPR002867 IBR domain
Domain IPR044066 TRIAD supradomain
Domain IPR045840 Ariadne domain
Domain IPR047555 E3 ubiquitin-protein ligase ARIH2, BRcat domain
Domain IPR047556 E3 ubiquitin-protein ligase TRIAD1, Rcat domain
Family IPR031127 E3 ubiquitin ligase RBR family
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length Ariadne domain E3 ubiquitin ligase RBR family E3 ubiquitin-protein ligase ARIH2, BRcat domain E3 ubiquitin-protein ligase TRIAD1, Rcat domain IBR domain TRIAD supradomain Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:Q7T355 492
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arih2-201 (1) Ensembl 2,394 nt
mRNA arih2-202 (1) Ensembl 753 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations