Gene
hacl1
- ID
- ZDB-GENE-040426-2058
- Name
- 2-hydroxyacyl-CoA lyase 1
- Symbol
- hacl1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have carbon-carbon lyase activity and thiamine pyrophosphate binding activity. Predicted to be involved in fatty acid alpha-oxidation. Predicted to localize to peroxisome. Orthologous to human HACL1 (2-hydroxyacyl-CoA lyase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Gao et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR011766 | Thiamine pyrophosphate enzyme, TPP-binding |
| Domain | IPR012000 | Thiamine pyrophosphate enzyme, central domain |
| Domain | IPR012001 | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain |
| Family | IPR045025 | TPP-binding domain containing protein HACL1-like |
| Homologous_superfamily | IPR029035 | DHS-like NAD/FAD-binding domain superfamily |
| Homologous_superfamily | IPR029061 | Thiamin diphosphate-binding fold |
Domain Details Per Protein
| Protein | Length | DHS-like NAD/FAD-binding domain superfamily | Thiamin diphosphate-binding fold | Thiamine pyrophosphate enzyme, central domain | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain | Thiamine pyrophosphate enzyme, TPP-binding | TPP-binding domain containing protein HACL1-like |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYI5
|
568 |
Interactions and Pathways
No data available
Plasmids
No data available