Gene

cdc20

ID

ZDB-GENE-040426-2044

Name

cell division cycle 20 homolog

Symbol

cdc20 Nomenclature History

Previous Names

wu:fe49f10
zgc:63536 (1)
zom (2)
zombie (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process and positive regulation of anaphase-promoting complex-dependent catabolic process. Predicted to act upstream of or within cell division and positive regulation of ubiquitin protein ligase activity. Predicted to be part of anaphase-promoting complex. Is expressed in proliferative region. Orthologous to human CDC20 (cell division cycle 20).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63536 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdc20 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Oocyte/zygote/embryo maturation arrest 14	620276

Associated With cdc20 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR024977	Anaphase-promoting complex subunit 4-like, WD40 domain
Family	IPR033010	WD repeat Cdc20/Fizzy
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Anaphase-promoting complex subunit 4-like, WD40 domain	Quinoprotein alcohol dehydrogenase-like superfamily	WD40 repeat	WD40 repeat, conserved site	WD40/YVTN repeat-like-containing domain superfamily	WD repeat Cdc20/Fizzy
UniProtKB:A0A0R4IU39 InterPro	496

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cdc20-201 (1) Ensembl	Ensembl	2,201 nt	Select Tool ZFIN BLAST
mRNA	cdc20-202 (1) Ensembl	Ensembl	893 nt	Select Tool ZFIN BLAST
mRNA	cdc20-204 (1) Ensembl	Ensembl	2,601 nt	Select Tool ZFIN BLAST
ncRNA	cdc20-003 (1) Ensembl	Ensembl	616 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations