Gene

med15

ID
ZDB-GENE-040426-2032
Name
mediator complex subunit 15
Symbol
med15 Nomenclature History
Previous Names
  • fi85b10
  • pcqap (1)
  • wu:fd19g01
  • wu:fi19d01
  • wu:fi85b10
  • zgc:55839
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and mediator complex. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MED15 (mediator complex subunit 15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Lin et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With med15 Human Ortholog
No data available
Associated With med15 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR019087 Mediator of RNA polymerase II transcription subunit 15, N-terminal
Domain IPR048385 ARC105/Med15 mediator subunit, central domain
Domain IPR048386 ARC105/Med15 mediator subunit, C-terminal domain
Homologous_superfamily IPR036529 Coactivator CBP, KIX domain superfamily
Domain Details Per Protein
Protein Length ARC105/Med15 mediator subunit, central domain ARC105/Med15 mediator subunit, C-terminal domain Coactivator CBP, KIX domain superfamily Mediator of RNA polymerase II transcription subunit 15, N-terminal
UniProtKB:A0A8M9PTS3 766
UniProtKB:A0A8M9PI73 801
UniProtKB:Q7ZVN7 809
UniProtKB:F1QFA9 802
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript med15-202 (1) Ensembl 643 nt
mRNA med15-201 (1) Ensembl 2,751 nt
mRNA med15-203 (1) Ensembl 489 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations