Gene
med15
- ID
- ZDB-GENE-040426-2032
- Name
- mediator complex subunit 15
- Symbol
- med15 Nomenclature History
- Previous Names
-
- fi85b10
- pcqap (1)
- wu:fd19g01
- wu:fi19d01
- wu:fi85b10
- zgc:55839
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and mediator complex. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MED15 (mediator complex subunit 15).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55839 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lin et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR019087 | Mediator of RNA polymerase II transcription subunit 15, N-terminal |
Domain | IPR048385 | ARC105/Med15 mediator subunit, central domain |
Domain | IPR048386 | ARC105/Med15 mediator subunit, C-terminal domain |
Homologous_superfamily | IPR036529 | Coactivator CBP, KIX domain superfamily |
Domain Details Per Protein
Protein | Length | ARC105/Med15 mediator subunit, central domain | ARC105/Med15 mediator subunit, C-terminal domain | Coactivator CBP, KIX domain superfamily | Mediator of RNA polymerase II transcription subunit 15, N-terminal |
---|---|---|---|---|---|
UniProtKB:A0A8M9PTS3
|
766 | ||||
UniProtKB:A0A8M9PI73
|
801 | ||||
UniProtKB:Q7ZVN7
|
809 | ||||
UniProtKB:F1QFA9
|
802 |
Interactions and Pathways
No data available
Plasmids
No data available