Gene

dhps

ID
ZDB-GENE-040426-2001
Name
deoxyhypusine synthase
Symbol
dhps Nomenclature History
Previous Names
  • wu:fb52g04
  • wu:fj48f12
  • zgc:111900
  • zgc:56018
  • zgc:77325
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have deoxyhypusine synthase activity. Involved in exocrine pancreas development and type B pancreatic cell development. Predicted to localize to cytoplasm. Is expressed in endoderm; intestine; liver; and pancreas. Orthologous to human DHPS (deoxyhypusine synthase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Mastracci et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dhps Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with seizures and speech and walking impairment 618480
Associated With dhps Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002773 Deoxyhypusine synthase
Homologous_superfamily IPR029035 DHS-like NAD/FAD-binding domain superfamily
Homologous_superfamily IPR036982 Deoxyhypusine synthase superfamily
Domain Details Per Protein
Protein Length Deoxyhypusine synthase Deoxyhypusine synthase superfamily DHS-like NAD/FAD-binding domain superfamily
UniProtKB:Q6NYK1 361
UniProtKB:Q567L8 297
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dhps-201 (1) Ensembl 2,199 nt
mRNA dhps-202 (1) Ensembl 713 nt
mRNA dhps-204 (1) Ensembl 1,087 nt
ncRNA dhps-002 (1) Ensembl 782 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations