Gene
katnb1
- ID
- ZDB-GENE-040426-1954
- Name
- katanin p80 (WD repeat containing) subunit B 1
- Symbol
- katnb1 Nomenclature History
- Previous Names
-
- wu:fj32f02
- wu:fj65h01 (1)
- zgc:56071
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to contribute to microtubule-severing ATPase activity. Involved in midbrain development. Predicted to localize to cytoplasm; katanin complex; and spindle pole. Human ortholog(s) of this gene implicated in lissencephaly. Is expressed in brain and pectoral fin. Orthologous to human KATNB1 (katanin regulatory subunit B1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139857 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lissencephaly 6 | Alliance | Lissencephaly 6, with microcephaly | 616212 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| idiopathic scoliosis | katnb1mh102/mh102 | standard conditions | Meyer-Miner et al., 2022 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR028021 | Katanin p80 subunit, C-terminal |
| Family | IPR026962 | Katanin p80 WD40 repeat-containing subunit B1 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | Katanin p80 subunit, C-terminal | Katanin p80 WD40 repeat-containing subunit B1 | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZUV2
|
694 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
katnb1-201
(1)
|
Ensembl | 2,572 nt | ||
| mRNA |
katnb1-202
(1)
|
Ensembl | 769 nt | ||
| mRNA |
katnb1-203
(1)
|
Ensembl | 741 nt | ||
| mRNA |
katnb1-206
(1)
|
Ensembl | 1,050 nt | ||
| ncRNA |
katnb1-004
(1)
|
Ensembl | 542 nt | ||
| ncRNA |
katnb1-005
(1)
|
Ensembl | 701 nt |
Interactions and Pathways
No data available
Plasmids
No data available