Gene
ndufb8
- ID
- ZDB-GENE-040426-1858
- Name
- NADH:ubiquinone oxidoreductase subunit B8
- Symbol
- ndufb8 Nomenclature History
- Previous Names
-
- nduf8
- zgc:77718
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Is expressed in skeletal muscle. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 32. Orthologous to human NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77718 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nuclear type mitochondrial complex I deficiency 32 | Alliance | Mitochondrial complex I deficiency, nuclear type 32 | 618252 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa |
|---|---|---|---|
|
UniProtKB:Q6P5L5
|
188 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndufb8-201
(1)
|
Ensembl | 665 nt | ||
| ncRNA |
ndufb8-002
(1)
|
Ensembl | 551 nt |
Interactions and Pathways
No data available
Plasmids
No data available