Gene
scp2a
- ID
- ZDB-GENE-040426-1846
- Name
- sterol carrier protein 2a
- Symbol
- scp2a Nomenclature History
- Previous Names
-
- scp2
- zgc:77634
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have transferase activity, transferring acyl groups other than amino-acyl groups. Predicted to be involved in positive regulation of intracellular cholesterol transport. Is expressed in intestinal bulb; lens; liver; and solid lens vesicle. Orthologous to human SCP2 (sterol carrier protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77634 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Leukoencephalopathy with dystonia and motor neuropathy | 613724 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR020615 | Thiolase, acyl-enzyme intermediate active site |
| Conserved_site | IPR020613 | Thiolase, conserved site |
| Domain | IPR003033 | SCP2 sterol-binding domain |
| Domain | IPR020616 | Thiolase, N-terminal |
| Homologous_superfamily | IPR016039 | Thiolase-like |
| Homologous_superfamily | IPR036527 | SCP2 sterol-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | SCP2 sterol-binding domain | SCP2 sterol-binding domain superfamily | Thiolase, acyl-enzyme intermediate active site | Thiolase, conserved site | Thiolase-like | Thiolase, N-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6P4V5
|
538 | ||||||
|
UniProtKB:A0A8M2BA96
|
332 |
Interactions and Pathways
No data available
Plasmids
No data available