Gene
uqcrc1
- ID
- ZDB-GENE-040426-1792
- Name
- ubiquinol-cytochrome c reductase core protein 1
- Symbol
- uqcrc1 Nomenclature History
- Previous Names
-
- zgc:73404 (1)
- zgc:85750
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have catalytic activity and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to localize to mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including cerebellum; epidermis; gut; inner ear; and liver and biliary system. Orthologous to human UQCRC1 (ubiquinol-cytochrome c reductase core protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85750 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Parkinsonism with polyneuropathy | 619279 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metalloenzyme, LuxS/M16 peptidase-like | Mitochondrial Processing Peptidase/Ubiquinol-cytochrome c Reductase Complex | Peptidase M16, C-terminal | Peptidase M16, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q6PBH6
|
474 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
uqcrc1-201
(1)
|
Ensembl | 1,897 nt | ||
| ncRNA |
uqcrc1-202
(1)
|
Ensembl | 1,682 nt |
Interactions and Pathways
No data available
Plasmids
No data available