Gene

pole3

ID
ZDB-GENE-040426-1773
Name
polymerase (DNA directed), epsilon 3 (p17 subunit)
Symbol
pole3 Nomenclature History
Previous Names
  • zgc:73351 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have chromatin DNA binding activity. Predicted to be involved in cellular response to DNA damage stimulus; chromatin remodeling; and leading strand elongation. Predicted to localize to CHRAC and epsilon DNA polymerase complex. Is expressed in alar plate midbrain region; immature eye; nervous system; pectoral fin; and pharyngeal arch 3-7 skeleton. Orthologous to human POLE3 (DNA polymerase epsilon 3, accessory subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pole3 Human Ortholog
No data available
Associated With pole3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain
Family IPR051377 DNA Polymerase Epsilon Subunit
Homologous_superfamily IPR009072 Histone-fold
Domain Details Per Protein
Protein Length DNA Polymerase Epsilon Subunit Histone-fold Transcription factor CBF/NF-Y/archaeal histone domain
UniProtKB:Q6PBL4 148
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pole3-201 (1) Ensembl 1,277 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations