Gene

gchfr

ID

ZDB-GENE-040426-1731

Name

GTP cyclohydrolase I feedback regulator

Symbol

gchfr Nomenclature History

Previous Names

zgc:73253

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have GTP cyclohydrolase binding activity. Predicted to be involved in negative regulation of GTP cyclohydrolase I activity. Predicted to localize to cytoplasm and nucleus. Is expressed in liver. Orthologous to human GCHFR (GTP cyclohydrolase I feedback regulator).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73253 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gchfr Human Ortholog

No data available

Associated With gchfr Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR009112	GTP cyclohydrolase I, feedback regulatory protein
Homologous_superfamily	IPR036717	GFRP superfamily

Domain Details Per Protein

Protein	Length	GFRP superfamily	GTP cyclohydrolase I, feedback regulatory protein
UniProtKB:A0A8M2B5F4 InterPro	88
UniProtKB:Q6PBT6 InterPro	89

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	gchfr-201 (1) Ensembl	Ensembl		778 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations